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Recombinant Human IL-1β Protein-T&L T&L

Name: Explore Recombinant Human IL-1β Protein-T&L T&L for more. Visit our store today and enjoy amazing savings
SKU: mode_7520367444149
Price: 72.00 USD
Availability: InStock

Original price was: $ 180,00.Current price is: $ 72,00.

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SKU: mode_7520367444149 Category: Uncategorized Tag: protein

Product Information

Construction	A DNA sequence encoding the IL-1β（GenBank: AAA72849.1）was expressed with a His-tag at the C-terminus
Expression Host	HEK293 cells
QC Testing Purity	> 90 % as determined by SDS-PAGE
Activity	Determined by the dose-dependent stimulation of the proliferation of D10 cells. The expected ED₅₀ for this effect is ≤ 0.1 ng/ml
Endotoxin	< 0.1 EU per 1 μg of the protein by the LAL method
Molecular Mass	The recombinant human IL-1β protein consists of 159 amino acids and predicts a molecular mass of 18.2 kD
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 6 % mannitol are added as protectants before lyophilization
Stability & Storage	24 months at 2℃ to 8℃ in lyophilized state. 6 months at -20℃ under sterile conditions after reconstitution. 12 months at -80℃ under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities after reconstituting with water for injection, normal saline or PBS, and keep the diluted concentration above 100μg/mL. Avoid repeated freeze-thaw cycles.

Background

IL-1 βis a pro-inflammatory cytokine produced in various cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. IL-1α and IL-1 β bind to the same receptor and have similar biological characteristics. These cytokines have a wide range of activities, including inducing IL-2 release to promote thymocyte proliferation, B cell maturation and proliferation, fibroblast growth factor like activity, and synovial cells releasing prostaglandins and collagenase. However, IL-1 β is a secreted cytokine, while IL-1α is mainly a cell related cytokine.

References

A mesenchymal stem cell line transplantation improves neurological function and angiogenesis in intraventricular amyloid β-infused rats.Haque A, Sheikh A, Mamun AA, Yano S, Hashimoto M, Shido O, Nagai A.Curr Alzheimer Res. 2018 Sep 11. doi: 10.2174/1567205015666180911145159.
Luteolin protects microglia against rotenone-induced toxicity in a hormetic manner through targeting oxidative stress response, genes associated with Parkinson’s disease and inflammatory pathways.Elmazoglu Z, Yar Saglam AS, Sonmez C, Karasu C.Drug Chem Toxicol. 2018 Sep 12:1-8. doi: 10.1080/01480545.2018.1504961.
Podocytes contribute, and respond, to the inflammatory environment in lupus nephritis.Wright RD, Beresford MW.Am J Physiol Renal Physiol. 2018 Sep 12. doi: 10.1152/ajprenal.00512.2017.

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Recombinant Human IL-1β Protein

Recombinant Human IL-1β Protein_SDS

Recombinant Human IL-1β Protein_COA_Pr2305009

Size	10μg, 100μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Recombinant Human IL-1β Protein-T&L T&L

Product Information

Background

References

Document

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