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Anti-Human CD52 mAb-T&L T&L

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SKU: mode_7510002368693
Price: 105.60 USD
Availability: InStock

Original price was: $ 352,00.Current price is: $ 105,60.

SKU: mode_7510002368693 Category: Uncategorized

Product Information

Expression Host	HEK293 cells
QC Testing Purity	> 90 % as determined by SDS-PAGE
Purification	Protein A purified from cell culture supernatan
Endotoxin Level	< 0.1 EU per μg of the protein as determined by the LAL method
Formulation	Supplied as a 0.22μm filtered solution in PBS, PH 7.4.
Stability & Storage	24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.

Background

CD52 is a widely distributed antigen belonging to a GPI anchored glycoprotein with only twelve amino acid residues (GQNDTSQTSSPS). CD52 can be found on the surface of lymphocytes, monocytes,eosophils and dendritic cells in hematopoietic system. With a density of up to 5×10⁵ molecules on lymphocytes, CD52 antigens express on many lymphoid cell malignancies and certain acute myeloid leukemia cells. When CD52 molecules are crosslinked with mAb, it triggers a series of signaling within the target cells. The signaling caused by the activation of CD52 molecules is similar to what caused by anti-CD3 antibodies. When CD52 molecules are triggered, PMA (Phorbol Myristate acetate, acetylmyridrobol ester) can promote the proliferation and secretion of cytokines in normal human CD4 + and CD8 + T lymphocytes in vitro.

References

Quigley MM, Bethel KJ, Sharpe RW.CD52 expression in hairy cell leukemia[ J]. Am J Hematol, 2003 , 74(4):227-230.
Rowan W, Tite J, Topley P .Cross-linking of the CAMPATH-1 antigen (CD52)mediates growth inhibition in human B- and T- lymphoma cell lines, and subsequent emergence of CD52-deficient cells[ J] .Immunology , 1998 ,95:427-436. [J]. Immunology, 1998,95:427-436.

Document

Anti-Human CD52 mAb

Anti-Human CD52 mAb_SDS

Size	100μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Anti-Human CD52 mAb-T&L T&L

Product Information

Background

References

Document

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