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Anti-Human CD20 mAb-T&L T&L

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SKU: mode_7510002303157
Price: 101.60 USD
Availability: InStock

Original price was: $ 254,00.Current price is: $ 101,60.

SKU: mode_7510002303157 Category: Uncategorized Tag: Antibody

Product Information

Expression Host	CHO cells
QC Testing Purity	> 90 % as determined by SDS-PAGE
Purification	Protein A purified from cell culture supernatant
Endotoxin Level	< 0.1 EU per μg of the protein as determined by the LAL method
Formulation	Supplied as a 0.22μm filtered solution in PBS, PH 7.4.
Stability & Storage	24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.

Background

CD20 is a specific signature molecule on the surface of B lymphocytes and is expressed on more than 95% of normal or malignant B lymphocytes. There is no expression of CD20 antigen in hematopoietic stem cells, progenitor cells, and other normal tissues. It consists of 297 amino acids with a molecular weight of 33 kD. CD20 has no internalization or cell surface shedding after binding with anti-CD20 mAb, which is an ideal antigen in the treatdment of B lymphocyte-related diseases. Anti-CD20 mAb can kill most of the lymphoma cells expressing CD20 molecules and normal B cells. Innate normal B cells are not affected by anti-CD20 mAb and can reconstruct B cell population. Therefore, anti-CD20 monoclonal antibodies are increasingly used in the treatment of B cell-related diseases.

References

Macardle PJ, Nicholson IC (2003). “CD20”. J. Biol. Regul. Homeost. Agents 16 (2): 136–8.PMID 12144126.
Tamayose K, Sato N, Ando J; et al. (2002). “CD3-negative, CD20-positive T-cell prolymphocytic leukemia: case report and review of the literature”. Am. J. Hematol. 71 (4): 331–5. doi:10.1002/ajh.10224. PMID 12447967.
Küster H, Zhang L, Brini AT; et al. (1992). “The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor”. J. Biol. Chem. 267 (18): 12782–7. PMID 1535625.

Document

Anti-Human CD20 mAb

Anti-Human CD20 mAb_SDS

Size	500μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Anti-Human CD20 mAb-T&L T&L

Product Information

Background

References

Document

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