Sale!

Anti-Human CD3 mAb-T&L T&L

Name: Buy the most recent Anti-Human CD3 mAb-T&L T&L models at amazing prices
SKU: mode_7510001025205
Price: 56.40 USD
Availability: InStock

Original price was: $ 141,00.Current price is: $ 56,40.

SKU: mode_7510001025205 Category: Uncategorized

Product Information

Expression Host	CHO cells
QC Testing Purity	> 95 % as determined by SDS-PAGE
Purification	Protein A purified from cell culture supernatant
Endotoxin Level	< 0.01 EU per μg of the protein as determined by the LAL method
Formulation	Supplied as a 0.22μm filtered solution in PBS, PH 7.4.
Stability & Storage	24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.
Applications	Soluble method: the concentration of 500 ng/mL is recommended, under which T cells can be activated and CD3+CD56+ T cells can be expanded significantly. Coating method: 10 mL PBS buffer (5 μg/mL anti-human CD3) is placed in a T75 flask at 4°C overnight. Please remove the PBS and wash the flask with saline gently three times before use.

Background

In immunology, CD3 (Differentiated Cluster 3) of T cells is a protein complex. CD3 has five peptide chains, namely, the γ, δ, ε, ζ, and η chains, all of which are transmembrane proteins. The transmembrane region of the CD3 molecule is connected to the transmembrane region of the two peptide chains of TCR through a salt bridge to form the TCR-CD3 complex, which jointly participates in the recognition of antigen. The activation signal generated by TCR antigen recognition is generated and transduced by CD3. Mononuclear cells isolated from peripheral blood, bone marrow, or umbilical cord blood can obtain large numbers of proliferating T lymphocytes in the presence of CD3 monoclonal antibodies and various cytokines.

References

Silvia M Bacot,Taylor A Harper,Rebecca L Matthews,Christie Jane Fennell,Adovi Akue, Mark A KuKuruga , Shiowjen Lee,Tao Wang,Gerald M Feldman.Exploring the Potential Use of a PBMC-Based Functional Assay to Identify Predictive Biomarkers for Anti-PD-1 Immunotherapy. Int J Mol Sci. 2020 Nov 27;21(23):9023.
Min Zhou, Jing Wang, Cui-Ping Li , Jing-Yan Xu,Bing Chen,Autologous Cytokine-Induced Killer Cell Immunotherapy for Patients with High-Risk Diffuse Large B Cell Lymphoma After the First Complete Remission. Onco Targets Ther. 2020 Jun 22;13:5879-5885.

Document

Anti-Human CD3 mAb

Anti-Human CD3 mAb_SDS

Anti-Human CD3 mAb_COA

Size	500μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Anti-Human CD3 mAb-T&L T&L

Product Information

Background

References

Document

Related products

Login