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Anti-Human CD28 mAb-T&L T&L

Name: A Wide Variety of Quality At Low Prices at Anti-Human CD28 mAb-T&L T&L
SKU: mode_7510001254581
Price: 56.40 USD
Availability: InStock

Original price was: $ 141,00.Current price is: $ 56,40.

SKU: mode_7510001254581 Category: Uncategorized

Product Information

Expression Host	Mouse Hybridoma cells
QC Testing Purity	> 95 % as determined by SDS-PAGE
Purification	Protein A purified from cell culture supernatant
Endotoxin Level	< 0.01 EU per μg of the protein as determined by the LAL method
Formulation	Supplied as a 0.22μm filtered solution in PBS, PH 7.4.
Stability & Storage	24 months at 2℃ to 8℃. Avoid repeated freeze-thaw cycles.
Applications	Soluble method: the concentration of 500 ng/mL is recommended, under which T cells can be activated and CD3+CD56+ T cells can be expanded significantly. Coating method: 10 mL PBS buffer (5μg/mL anti-human CD3) is placed in a T75 flask at 4°C overnight. Please remove the PBS and wash the flask with saline gently three times before use.

Background

The CD28 molecules express on the surface of most T cells and is considered to be unique to T cells. T cell reactivity to antigen is mainly mediated through the CD3 / TCR complex, but also depends on the synergy of other molecules. T cells can be efficiently activated by several pathways, including CD3 / TCR, CD2, and CD28. Mononuclear cells isolated from peripheral blood, bone marrow or cord blood can be the source of T cells proliferation in the presence of CD3, CD28 monoclonal antibodies and various other cytokines.

References

Daniel Teschner , Gregor Wenzel , Eva Distler , Elke Schnürer , Matthias Theobald , AxlA Neurauter , Karoline Schjetne and Wolfgang Herr. In vitro stimulation and expansion of human tumor-reactive CD8+cytotoxic T-lymphocytes by anti-CD3/CD28/CD137 magnetic beads .Scandinavian Journal of Immunology 2011, 74(2):155–164.
D Sangiolo, G Mesiano, F Carnevale-Schianca, W Piacibello, M Aglietta & A Cignetti . Cytokine induced killer cells as adoptive immunotherapy strategy to augment graft versus tumor after hematopoietic cell transplantation. Expert Opin. Biol. Ther. (2009) 9(7):831-840.
RENATE SIEFKEN, ROLAND KURRLE, AND REINHARD SCHWINZER.CD28-Mediated Activation of Resting Human T Cells without Costimulation of the CD3/TCR Complex. CELLULAR IMMUNOLOGY 176, 59–65 (1997).

Document

Anti-Human CD28 mAb

Anti-Human CD28 mAb_SDS

Size	500μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Anti-Human CD28 mAb-T&L T&L

Product Information

Background

References

Document

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