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Recombinant Human IFN-γ Protein-T&L T&L

Name: Discover our range of Recombinant Human IFN-γ Protein-T&L T&L at affordable prices
SKU: mode_7520365576373
Price: 42.50 USD
Availability: InStock

Original price was: $ 85,00.Current price is: $ 42,50.

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Clear

SKU: mode_7520365576373 Category: Uncategorized Tag: protein

Product Information

Protein sequence	Accession # AAH70256 Q24-Q166
Expression Host	HEK293 cells
QC Testing Purity	> 90 % as determined by SDS-PAGE
Activity	Measured in anti-viral assays protecting human amniotic cells (WISH) from the destructive effects of vesicular stomatitis virus (VSV). The ED₅₀ for this effect is ≤50 ng/mL
Endotoxin Level	< 0.1 EU per 1 μg of the protein by the LAL method
Molecular Mass	Predicts a molecular mass of 17.6 kD
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 6 % mannitol are added as protectants before lyophilization
Stability & Storage	24 months at 2 °C to 8 °C in lyophilized state. 6 months at -20 °C under sterile conditions after reconstitution. 12 months at -80 °C under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities after reconstituting with water for injection, normal saline or PBS, and keep the diluted concentration above 100 µg/mL. Avoid repeated freeze-thaw cycles.

Background

IFN-γ is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. IFN-γ exerts a wide range of immunoregulatory activities and plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, up-regulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-γ has a strong inhibitory effect on the activation, proliferation and secretion of extracellular matrix of hepatic stellate cells (HSC), and it can inhibit collagen synthesis and promote collagen degradation.

References

Wang Y, Dai H, Li H, Lv HY,Wang T, Fu XB,and Han WD (2011) Growth of Human Colorectal Cancer SW1116 Cells Is Inhibited by Cytokine-Induced Killer Cells. Clinical and Developmental Immunology 2011 (1740-2522):621414.
Sangiolo D, Mesiano G, F Carnevale-Schianca, W Piacibello, M Aglietta and A Cignetti (2009) Cytokine induced killer cells as adoptive immunotherapy strategy to augment graft versus tumor after hematopoietic cell transplantation. Expert Opin. Biol. Ther. 9(7):831-840.

Document

Recombinant Human IFN-γ Protein

Recombinant Human IFN-γ Protein_SDS

Recombinant Human IFN-γ Protein_COA

Size	200μg

Quick Shipping and Professional Packaging

We can offer a variety of shipping options due to our long-term relationship with UPS FedEx DHL. Our warehouse staff will package each item according to our strict specifications. Your products will be subjected to a thorough examination and will be safely packaged prior to being shipped. Everyday we deliver thousands of packages to clients across many countries. This is a sign of our determination to become the biggest online retailer in the world. There are distribution centers and warehouses in Europe as well as the USA.

Orders that contain more than 1 item are given processing time for each item.

Before shipment, all ordered items will be thoroughly inspected. Most orders are shipped within 48-hours. Delivery is expected to take between 3 and 7 days.

Returns

The stock market is always changing. It is not managed entirely by us, as we're involved with several parties such as the factory and our storage. The levels of stock can change at any given time. Be aware that it is possible for your order to run out of stock even after you have placed the order.

The policy is 30 days. However, if 30 days have passed since you purchased your item, we will not be able to offer you a return or exchange.

To be eligible for a refund the item must be in good condition and in the same state as when you received it. It should also be in the original package.

Recombinant Human IFN-γ Protein-T&L T&L

Product Information

Background

References

Document

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